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It takes 300 screening mammograms to discover one woman with breast cancer. A breath test might improve this very low yield. Researchers have known for many years that women with breast cancer have abnormal volatile organic compounds (VOCs) in their breath. Clinical studies at Menssana Research have shown that these breath VOCs can accurately identify women with early stage breast cancer or an abnormal screening mammogram. The National Cancer Institute is funding a multicenter clinical study to validate BreathLink and BreathBag for early detection of breast cancer. A breath test that identifies women at low risk of breast cancer could potentially reduce the number of needless screening mammograms and breast biopsies. Eventually, women may be able to screen themselves for breast cancer at home with the BreathX system. https://clinicaltrials.gov/ct2/show/NCT02888366 https://www.cbsnews.com/news/on-the-horizon-breathlink-cancer-breath-test/ Publications (PDF Document) Prediction of breast cancer risk with volatile biomarkers in breath. Phillips M, Cataneo RN, Cruz-Ramos JA, Huston J, Ornelas O, Pappas N, Pathak S.Breast Cancer Research and Treatment (17 Mar. 2018)(PDF Document) Breath mass ion biomarkers of breast cancer. Phillips M, Cataneo RN, Lebauer C, Mundada M, Saunders C.Journal of Breath Research (19 Dec. 2016)(PDF Document) Rapid Point-Of-Care Breath Test for Biomarkers of Breast Cancer and Abnormal Mammograms. Phillips M, Beatty JD, Cataneo RN, Huston J, Kaplan PD, Lalisang RI, Lambin P, Lobbes MBI, Mundada M, Pappas N, Patel U.PLOS ONE (Mar. 5, 2014)(PDF Document) Volatile biomarkers in the breath of women with breast cancer. Phillips M, Cataneo RN, Saunders C, Hope P, Schmitt P, and Wai J .Journal of Breath Research (Mar. 2, 2010) |
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